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KMID : 1100920190400060399
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Korean Journal of Family Medicine
2019 Volume.40 No. 6 p.399 ~ p.405
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Relationship between Alcohol Consumption and Ocular Pressure according to Facial Flushing in Korean Men with Obesity
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Lee Sa-Mi
Kim Jong-Sung
Kim Sung-Soo
Jung Jin-Gyu
Yoon Seok-Joon
Seo Yu-Ri
Kim Ji-Han
Bae Yoon-Kyung
Lee Ja-Young
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Abstract
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Background: This study aimed to examine the relationship between alcohol consumption and intraocular pressure (IOP) according to facial flushing in Korean men with obesity.
Methods: The study included 479 Korean men with a body mass index of ≥25 kg/m2 (75 non-drinkers, 174 with drinking-related facial flushing, and 230 without facial flushing) who underwent health check-ups between October 1, 2016 and March 31, 2017. Multivariate logistic regression was used to assess the relationship between alcohol consumption and high IOP (≥21 mm Hg).
Results: Flushers consuming ≤16 drinks per week had a significantly higher risk of high IOP than non-drinkers, depending on alcohol consumption (≤8 standard drinks: odds ratio [OR], 4.49; 95% confidence interval [CI], 1.05? 19.25; >8 but ≤16 standard drinks: OR, 8.14; 95% CI, 1.37?48.45). However, when the consumption was >16 drinks per week, the high IOP risk did not significantly increase (OR, 0.71; 95% CI, 0.05?10.69). In addition, there was no significant relationship between alcohol consumption and high IOP among non-flushers consuming ≤8 drinks per week (OR, 2.07; 95% CI, 0.52?8.19). However, a significantly increased risk of high IOP was observed among non-flushers consuming >8 drinks per week, depending on alcohol consumption (>8 but ≤16 standard drinks: OR, 4.84; 95% CI, 1.14?20.61; >16 standard drinks: OR, 4.08; 95% CI, 1.02?16.26).
Conclusion: This study suggests that obese men with alcohol flush reactions may have an increased risk of high IOP with the consumption of smaller amounts of alcohol than non-flushers.
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KEYWORD
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Alcohol Drinking, Flushing, Intraocular Pressure, Obesity
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